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Twenty-five years after a streak of brutal murders shocked the quiet town of Woodsboro, a terrifying new killer resurrects the Ghostface mask. As the deaths mount, Woodsboro's new targets must seek help from the survivors of the original Ghostface attacks. Now, only Sidney Prescott (Neve Campbell), former sheriff Dewey Riley (David Arquette), and reporter Gale Weathers (Courteney Cox) can find a way to stop the killer when everyone is a suspect.